MOPS (3-(N-morpholino)propanesulfonic acid) is a buffer introduced by Good et al. in the 1960s. It is a structural analog to MES.Its chemical structure contains a morpholine ring. HEPES is a similar pH buffering compound that contains a piperazine ring. With a pKa of 7.20, MOPS is an excellent buffer for many biological systems at near-neutral pH.

MOPS | Basic Information
Product name	MOPS
Synonyms	3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid
CAS	1132-61-2
Molecular Formula	C7H15NO4S
Molecular weight	209.26
Hazard Codes	Xi:Irritant
Risk Statements	R36/37/38;
Safety Statements	S26; S36;

MOPS has been used as:

• a cell culture additive component in lentiviral particle production.

• as a buffering agent in microbial growth medium and nuclei extraction buffer.

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